The total body dynamic PET scans could be used to detect metastatic cancer successfully. Dynamic PET provides parametric images showing the actual behavior of the tissue.

The parametric images can potentially help to detect lesions and evaluate the response of cancer to therapy.But this potential has not been within the clinic, as conventional PET scanners don’t have a strong axial field-of-view and can’t perform simultaneous imaging of lesions in different parts of the body.

The focus of the study was to test the ability of kinetic modeling and parametricimaging of cancer. Various kinetic parameters can be combined to help understand how tumor metastases and various organs, such as the bone marrow and spleen behave.

Research Findings

A renal cell cancer patient went through a total-body PET scanner. Multiple cancer spreads were identified, proving that a total-body kinetic scan is possible, and it gives parametric imaging of metastatic cancer. 

Images showing glucose invasion and tumor were of enhanced contrast, leading to better visibility of cancer detection in the liver. 

A total-body PET scan also delivered multiple and quality descriptions of how the tumor spreads to different organs.

The total-body parametric imaging method is not limited but applies to all radio transmitters.

The scan is not just used for cancer, but it is also used to evaluate many other diseases too. PET scan quality images enable the genetic study of tissue and its behavior to be assessed in the same clinic.

Dynamic imaging and modeling enabled by (total-body PET) are likely to change fissionable medicine into this imaging method. In other words, many different aspects of tissue behavior can be assessed in the same clinical setting.